Ngezimonyo ezingokwemvelo, eziluhlaza, ezinempilo neziphephile ezinokukhishwa kwezitshalo eziheha ukunakwa okwengeziwe, ukuthuthukiswa kwezinto ezisebenzayo ezivela ezimisweni zezitshalo kanye nokuthuthukiswa kwezimo zezimo zemvelo ezihlanzekile sekube sezingcingo ezisebenzayo ekwakhiweni komkhakha wezimonyo. Ukuthuthukisa kabusha izinsizakusebenza zezitshalo akuyona nje ukubuyisela umlando, kepha ukusekela amasiko endabuko yaseChinese, futhi kuhlanganiswe imibono yendabuko yemithi yendabuko yaseChina, futhi isebenzise ubuchwepheshe besimanje be-biochemical ukuthuthukisa izinhlobo ezintsha zezimonyo zezitshalo, ukuze kuthuthukiswe ngokwesayensi futhi kuphephile izimonyo zemvelo. Imikhiqizo yamakhemikhali ihlinzeka ngezinto eziluhlaza eziluhlaza. Ngaphezu kwalokho, okukhishwa kwezitshalo kusetshenziswa kabanzi kwezokwelapha, izithasiselo zokudla, ukudla okusebenzayo, iziphuzo, izimonyo kanye nezinye izinkambu.
Izitshalo ezikhishwe. Izimonyo ezakhiwe ngesitsha sezitshalo njengezithako ezisebenzayo zinezinzuzo eziningi eziqhathaniswa nezimonyo zendabuko: Inqoba ukushiyeka kwezimonyo zendabuko ezincike kumakhemikhali, okwenza umkhiqizo uphephe; Izakhi zemvelo zidonswa kalula yisikhumba, okwenza umkhiqizo uphumelele ngokwengeziwe futhi umphumela ubaluleke kakhulu; Umsebenzi uvelele ngokwengeziwe, njll.
Ukukhetha ukukhishwa kwesitshalo esifanele nokwengeza inani elifanele lesitshalo esikhishwe kwimikhiqizo yezimonyo kungandisa umphumela wayo. Imisebenzi esemqoka yokukhishwa kwezitshalo ku-cosmetics yilezi: ukujuluka, ukususwa kokuguga, ukususwa kwe-freckle, ukuvikelwa kwelanga, kanye nokukhishwa kwezitshalo kuluhlaza futhi kuphephile.
MUmphumela we-Oisturing
Izakhiwo ze-moisturizing kwezimonyo ikakhulukazi zenziwa ngezindlela ezimbili: umuntu atholakala ngomphumela wokukhiya amanzi athola amabhondi e-hydrogen phakathi kwama-agent angumenzeli nama-molecule wamanzi; Okunye ukuthi amafutha akha ifilimu elivaliwe endaweni yesikhumba.
Izimonyo ezibizwa ngokuthi ama-mosmetics yizimonyo eziqukethe izithako ezinomswakama ukuze zilondoloze umswakama we-stratum Corneum ukuze ubuyisele i-lusterster kanye nokuqina kwesikhumba. Izimonyo ezinomswakama zihlukaniswe ngezinhlobo ezimbili ngokuya ngezimpawu zazo: eyodwa ukusebenzisa izinto ezigcina amanzi ezingahlanganiswa kakhulu umswakama ngaphezulu kwesikhumba i-stratum Corneum, ebizwa ngokuthi ama-glycerin; Enye into eyinto engafakwanga emanzini, kwakhiwa ungqimba lwefilimu lokugcoba ebusweni besikhumba, esisebenza njengesibonakaliso sokuvikela ukulahleka kwamanzi, ukuze i-stratum Corneum igcinwe umswakama othile, obizwa ngokuthi ama-emollients noma Ama-conditioners, anjengophethiloli, uwoyela, nama-waxes.
Kunezitshalo ezimbalwa ezimbalwa esitshalweni esinomphumela we-hydrating kanye ne-moisturizing, njenge-aloe vera, olwandle, umnqumo, umnqumo, umnqumo, wonke anomphumela omuhle wokuswakama.
Umphumela wokulwa nokuguga
Ngokunyuka kweminyaka, isikhumba siqala ukukhombisa isimo sokuguga, okubandakanya ngokukhethekile ukuncishiswa kwe-collagen, i-elastin, i-mucopolysaccharide nokunye okuqukethwe esikhunjeni ngamazinga ahlukahlukene, ukuqina kwegazi komsoco Udonga luyancipha, futhi isikhumba se-epidermis kancane kancane. Ukuncishiswa kwamafutha, okufihliwe, nokubukeka kwemibimbi, i-chloasma kanye namabala weminyaka.
Njengamanje, izifundo ezedlule ezenzweni zokuguga kwabantu zifingqe lezi zinto ezilandelayo:
Enye ukwanda nokuguga kwama-radicals wamahhala. Ama-radicals wamahhala ama-athomu noma ama-molecule anama-elektroni angatholakali akhiqizwa yi-homolysis ama-combared bond ama-combared. Bane-degree ephezulu yemisebenzi yamakhemikhali futhi baye bathola i-peroxidation enama-lipid angafakwanga. Lipid peroxide (LPO), and its final product, malondialdehyde (MDA), can react with most substances in living cells, resulting in reduced biofilm permeability, damage to DNA molecules, and cell death or mutation .
Okwesibili, imisebe ye-UVB ne-UVA ekukhanyiseni kwelanga ingadala ukutholakala kwezikhumba. Imisebe ye-Ultraviolet ikakhulukazi ibangela ukuguga kwesikhumba ngezinqubo ezilandelayo: 1) ukulimala kwe-DNA; 2) ukuxhumeka kwesiphambano se-collagen; 3) Ukwehliswa kokuphendula komzimba ngokufaka indlela evilitory yokuphendula okuvuselelwa kwe-antigen; 4) Isizukulwane sezinto ezisebenzayo ezisebenzayo zamahhala ezisebenzisana nezinhlaka ezahlukahlukene ze-intracellur 5. Vimbela ngqo umsebenzi wamaseli we-epidermal Langerhan, ebangela i-PhideImmunosupEpression futhi wenze buthaka umsebenzi wokuzivikela kwesikhumba. Ngaphezu kwalokho, i-glycosyaltation engeyona eye-enzymatic, ukuphazamiseka kwe-metabolic, kanye ne-matrix metallocropoRease ageing kuzothinta ukuguga kwesikhumba.
Izitshalo ezikhishwe njengoba ama-elastase e-Elastase Evitor abe yisihloko sokucwaninga esishisayo eminyakeni yamuva, njenge-Scutellaria Baizoensis, i-Burnet, uMorinda Citifsholia imbewu, iMoringa, Shuihe, i-Fortsthhia, iSalvia, Angelica nokunye. Imiphumela yocwaningo ikhombisa ukuthi: I-Salvia miltiorrrriza ekhishwe (i-ESM) ingavusa isisho seFilaggrin kuma-filatinocys ajwayelekile womuntu kanye ne-hydration, futhi akwazi ukuthuthukisa umsebenzi wokumelana nokuguga nokuthambekela ; Ukusuka ezitshalweni ezidliwayo khipha i-anti-free anti-free radical dpph, futhi uyisebenzise kwimikhiqizo efanelezo yezimonyo, ngemiphumela emihle; I-Polygonum Cuspidatum Extract inethonya elithile elivimbela ku-Elastase, ngaleyo ndlela anti-anti-aguga
Fhlanganisa
Umehluko wombala wesikhumba womzimba womuntu uvame ukuncika kokuqukethwe kanye nokusatshalaliswa kwe-epidermal melanin, ukujikeleza kwegazi kwe-dermis, kanye nobukhulu be-stratum corneum. Ukumnyama kwesikhumba noma ukwakheka kwezindawo ezimnyama kuthinteka kakhulu ekuqongeleleni kwenani elikhulu le-melanin, i-oxidation yesikhumba, ukuncishiswa kwe-keratinocyte, ukunqwabelanisa kwesikhumba okumpofu, nokuqongelela ubuthi emzimbeni.
Kulezi zinsuku, umphumela wokususwa kwe-freckle utholakala kakhulu ngokuthinta ukwakheka nokwanda kwe-melanin. Eyodwa yi-tyrosinase inhibitor. Ekuguqukeni kusuka ku-tyrosine kuya ku-dopa ne-dopa kuya ku-dopaquequinone, bobabili bahlaselwe yi-tyrominase, okulawula ngokuqondile ukusungulwa kanye nejubane lokuqalwa kwe-melanin, futhi kunquma ukuthi ngabe izinyathelo ezilandelayo zingaqhubeka.
Lapho izinto ezahlukahlukene zisebenza eTyrosinase ukwandisa umsebenzi wazo, ukuhlanganiswa kwe-melanin kwanda, kwathi lapho umsebenzi we-tyrosinase uvinjelwe, ukuhlanganiswa kwe-melanin kuyancipha. Ucwaningo luye lwabonisa ukuthi i-Arbutin ingavimbela umsebenzi weTyrosinase ebangeni lokuhlushwa ngaphandle kobuthi be-melanocyte, vimba ukuhlanganiswa kwe-dopa, futhi ngaleyo ndlela kuvimbele ukukhiqizwa kuka-melanin. Abaphenyi bafunda amakhemikhali wamakhemikhali e-Black Tiger Rhizomes kanye nemiphumela yawo mhlophe, ngenkathi ehlola ukucasuka kwesikhumba.
Imiphumela yocwaningo ikhombisa ukuthi: Phakathi kwamakhompiyutha ayi-17 angawodwa (HLH-1 ~ 17), i-HLH-3 ingavimba umphumela wokuthuthumela, futhi ukukhipha kucasule kakhulu esikhunjeni. Ren hongrong et al. Uveze ngokuhlolwa okukhishwa yi-lotus alcohol accoul kunomthelela omkhulu wokuvimbela ekwakhiweni kwe-melanin. Njengohlobo olusha lwe-ejenti yamhlophe ethathwe izitshalo, ingahlanganiswa kukhilimu ofanele futhi ingenziwa ekunakekelweni kwesikhumba, ukukhishwa okudala nokususa i-freckle. Izimonyo ezisebenzayo.
Kukhona futhi i-melanocyte cytotoxic ejenti, enjenge-Endothelin Naturances etholakala ezitshalweni zezitshalo, ezingavimbela ukuncintisana kwe-endothelin kuma-melanocyte membrane receptors, ukuze ihlukanise imisebe ye-ultraviolet ifaka inhloso ye-melanin ukukhiqiza. Ngokusebenzisa izivivinyo zeseli, frédéric bonté et al. kukhombisile ukuthi i-archid entsha ye-archid ikhishwe ingavimba ngempumelelo ukwanda kwama-melanocytes. Ukungeza ekwakhiweni kwezimonyo ezifanele kunemiphumela ebonakalayo ekunciphiseni isikhumba nokukhanyisa. Zhang mu et al. kukhishwe futhi kwafundwa ama-Chinese herbal akhishwe njenge-scutellaria Baizolia, i-polygonum cuspidatum kanye umngcele, futhi imiphumela yakhombisa ukuthi ukukhishwa kwazo kwe-lyrosinase, futhi kuncishiswe kakhulu okuqukethwe kwe-intracellular, ukuze kuncishiswe kakhulu umphumela we-freckle whitening.
Ukuvikelwa kwelanga
Ngokuvamile, ama-sunscreens asetshenziswa kakhulu ezimotweni zesikrini saseSunnscreen ahlukaniswe izigaba ezimbili: Omunye unama-UV atholakalayo, okuyizinhlanganisela ze-organic, ezinjenge-ketones; Enye yi-UV evikelekile ama-ejenti, okungukuthi, ama-sunnsry angokomzimba, njenge-tio2, zno. Kepha lezi zinhlobo ezimbili zama-sunscreens zingadala ukucasuka kwesikhumba, ukuhlukunyezwa kwesikhumba, nama-pores wesikhumba avalekile. Kodwa-ke, izitshalo eziningi zemvelo zinomphumela omuhle wokumuncwana kuma-rays we-ultraviolet, futhi ziqinisa ngokungaqondile ukusebenza kwezikrini ze-sunscreen zemikhiqizo ngokunciphisa ukulimala kwemisebe okubangelwa imisebe ye-ultraviolet esikhunjeni.
Ngaphezu kwalokho, izithako ze-sunscreen ezitshalweni zezitshalo zinezinzuzo zokucasuka kwesikhumba okuncane, ukuqina kwe-Photochemical, ukuphepha kanye nokwethenjwa kuqhathaniswa namakhemikhali e-sunscree endabuko. Zheng hongyan et al. Izithombo zezitshalo ezintathu ezikhethiwe, i-cortex, i-resveratrol, i-resveratrol kanye ne-arbutin, futhi zifundze imiphumela yokuvikelwa kanye ne-UVB kanye ne-UVA imiphumela yezimonyo zabo zelanga. Imiphumela yocwaningo ikhombisa ukuthi: Ezinye izitshalo zemvelo zibonisa umphumela omuhle wokuvikelwa we-UV. Inkomba kanye nabanye basebenzisa ama-travonouat we-tartary bullengwheat njengezinto zokwakha ezivuthiwe ukutadisha izakhiwo ze-sunscreen zama-flavonoids. Ucwaningo luthole ukuthi ukusetshenziswa kwama-flavonoids kuya kuma-emulsions angempela kanye nokuhlanganisa ama-suncreen ngokomzimba nakokhemikhali kunikeze isisekelo sethiyori sokusetshenziswa kwezimonyo ngokuzayo.
Xhumana nathi ngophenyo:
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Isikhathi sePosi: Jul-12-2022