Abantu abaningi bajwayelene ne-Parkinson kanye ne-Alzheimer's.Isifo sikaParkinson yisifo esivamile se-neurodegenerative.Kuvame kakhulu kubantu asebekhulile.Isilinganiso seminyaka yokuqala sineminyaka engaba ngu-60.Intsha eqala ukugula iParkinson’s engaphansi kweminyaka engama-40 ayivamile.Ukusabalala kwe-PD phakathi kwabantu abangaphezu kweminyaka engama-65 e-China cishe ku-1.7%.Iziguli eziningi ezinesifo sikaParkinson ziyenzeka ngezikhathi ezithile, futhi ngaphansi kuka-10% weziguli ezinomlando womndeni.Ushintsho olubaluleke kakhulu lwe-pathological ku-Parkinson's isifo ukuwohloka nokufa kwama-neurons e-dopaminergic ku-substantia nigra yobuchopho obuphakathi.Isizathu esiqondile salolu shintsho lwe-pathological ayikacaci.Izici zofuzo, izici zemvelo, ukuguga, kanye nengcindezi ye-oxidative konke kungase kuhileleke ekuwohlokeni nasekufeni kwe-PH dopaminergic neurons.Ukubonakaliswa kwayo kwemitholampilo ikakhulukazi kuhlanganisa ukuthuthumela kokuphumula, i-bradykinesia, i-myotonia kanye nokuphazamiseka kwe-postural gait, kuyilapho iziguli zingase zihambisane nezimpawu ezingezona izimoto ezifana nokucindezeleka, ukuqunjelwa kanye nokuphazamiseka kokulala.
I-Dementia, eyaziwa nangokuthi isifo i-Alzheimer's, yisifo se-neurodegenerative esithuthukayo esiqala ngobuqili.Ngokomtholampilo, kubonakala ngokuwohloka komqondo okuvamile, okufana nokukhubazeka kwenkumbulo, i-aphasia, i-apraxia, i-agnosia, ukonakala kwamakhono e-visuospatial, ukungasebenzi kahle kokuphatha, kanye nezinguquko kubuntu nokuziphatha.Labo abaqala ngaphambi kweminyaka yobudala engama-65 babizwa nge-Alzheimer's;labo abaqala ngemva kweminyaka engu-65 babizwa ngokuthi i-Alzheimer's.
Lezi zifo ezimbili zivame ukuhlupha abantu asebekhulile futhi zenza izingane zikhathazeke kakhulu.Ngakho-ke, indlela yokuvimbela ukwenzeka kwalezi zifo ezimbili bekulokhu kuyisizinda socwaningo sezazi.I-China iyizwe elikhulu lokukhiqiza itiye nokuphuza itiye.Ngaphezu kokuhlanza uwoyela kanye nokukhulula amafutha, itiye linenzuzo engalindelekile, okungukuthi, lingavimbela isifo sikaParkinson nesifo i-Alzheimer's.
Itiye elihlaza liqukethe isithako esisebenzayo esibaluleke kakhulu: i-epigallocatechin gallate, eyisithako esisebenzayo esisebenza kakhulu kuma-polyphenols etiye futhi ingeyakhathekhini.
Ucwaningo oluningi luye lwabonisa ukuthi i-epigallocatechin gallate ivikela izinzwa ekulimaleni kwezifo ze-neurodeergenerative.Ucwaningo lwesimanje lwe-epidemiological lubonise ukuthi ukuphuza itiye kuhlobene kabi nokuvela kwezinye izifo ze-neurodegenerative, ngakho-ke kucatshangwa ukuthi ukuphuza itiye kungase kusebenze ezinye izindlela zokuzivikela ezingapheli kumaseli e-neuronal.I-EGCG nayo inomphumela wokuqeda ukucindezeleka, futhi umsebenzi wayo wokuqeda ukucindezeleka ikakhulukazi uhlobene nokusebenzelana kwe-γ-aminobutyric acid receptors.Kubantu abane-HIV, i-neurodementia ebangelwa yigciwane iyindlela ye-pathogenic, futhi ucwaningo lwakamuva lubonise ukuthi i-EGCG ingavimbela le nqubo ye-pathological.
I-EGCG itholakala ikakhulukazi itiye elihlaza, kodwa hhayi itiye elimnyama, ngakho-ke inkomishi yetiye ecacile ngemva kokudla ingasusa amafutha futhi ikhulule ama-greasy, anempilo kakhulu.I-EGCE ekhishwe itiye eluhlaza ingasetshenziswa emikhiqizweni yezempilo kanye nezithako zokudla, futhi iyithuluzi elihle lokuvimbela izifo ezibalwe ngenhla.
Isikhathi sokuthumela: Apr-06-2022
